| Title |
Living well after breast cancer randomized controlled trial protocol: evaluating a telephone-delivered weight loss intervention versus usual care in women following treatment for breast cancer
|
|---|---|
| Published in |
BMC Cancer, October 2016
|
| DOI | 10.1186/s12885-016-2858-0 |
| Pubmed ID | |
| Authors |
Marina M. Reeves, Caroline O. Terranova, Jane M. Erickson, Jennifer R. Job, Denise S. K. Brookes, Nicole McCarthy, Ingrid J. Hickman, Sheleigh P. Lawler, Brianna S. Fjeldsoe, Genevieve N. Healy, Elisabeth A. H. Winkler, Monika Janda, J. Lennert Veerman, Robert S. Ware, Johannes B. Prins, Theo Vos, Wendy Demark-Wahnefried, Elizabeth G. Eakin |
| Abstract |
Obesity, physical inactivity and poor diet quality have been associated with increased risk of breast cancer-specific and all-cause mortality as well as treatment-related side-effects in breast cancer survivors. Weight loss intervention trials in breast cancer survivors have shown that weight loss is safe and achievable; however, few studies have examined the benefits of such interventions on a broad range of outcomes and few have examined factors important to translation (e.g. feasible delivery method for scaling up, assessment of sustained changes, cost-effectiveness). The Living Well after Breast Cancer randomized controlled trial aims to evaluate a 12-month telephone-delivered weight loss intervention (versus usual care) on weight change and a range of secondary outcomes including cost-effectiveness. Women (18-75 years; body mass index 25-45 kg/m(2)) diagnosed with stage I-III breast cancer in the previous 2 years are recruited from public and private hospitals and through the state-based cancer registry (target n = 156). Following baseline assessment, participants are randomized 1:1 to either a 12-month telephone-delivered weight loss intervention (targeting diet and physical activity) or usual care. Data are collected at baseline, 6-months (mid-intervention), 12-months (end-of-intervention) and 18-months (maintenance). The primary outcome is change in weight at 12-months. Secondary outcomes are changes in body composition, bone mineral density, cardio-metabolic and cancer-related biomarkers, metabolic health and chronic disease risk, physical function, patient-reported outcomes (quality of life, fatigue, menopausal symptoms, body image, fear of cancer recurrence) and behaviors (dietary intake, physical activity, sitting time). Data collected at 18-months will be used to assess whether outcomes achieved at end-of-intervention are sustained six months after intervention completion. Cost-effectiveness will be assessed, as will mediators and moderators of intervention effects. This trial will provide evidence needed to inform the wide-scale provision of weight loss, physical activity and dietary interventions as part of routine survivorship care for breast cancer survivors. Australian and New Zealand Clinical Trial Registry (ANZCTR) - ACTRN12612000997853 (Registered 18 September 2012). |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 386 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 386 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 58 | 15% |
| Student > Bachelor | 47 | 12% |
| Researcher | 42 | 11% |
| Student > Ph. D. Student | 34 | 9% |
| Student > Doctoral Student | 15 | 4% |
| Other | 57 | 15% |
| Unknown | 133 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 72 | 19% |
| Nursing and Health Professions | 70 | 18% |
| Sports and Recreations | 20 | 5% |
| Psychology | 19 | 5% |
| Social Sciences | 13 | 3% |
| Other | 43 | 11% |
| Unknown | 149 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2016.
All research outputs
#13,386,611
of 22,899,952 outputs
Outputs from BMC Cancer
#2,931
of 8,328 outputs
Outputs of similar age
#162,877
of 313,742 outputs
Outputs of similar age from BMC Cancer
#43
of 129 outputs
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We're also able to compare this research output to 129 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.